新利18体育官网登录网址情况简介
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【近5年来主要研究课题】 1.非病毒载体（超分子纳米粒子）用于CRISPR/Cas9基因编辑领域治疗多种单基因疾病包括先天性视网膜裂损症、镰刀型贫血症、地中海贫血症和杜氏肌营养不良症等。 2.超分子纳米粒子用于药物传输领域，通过纹身的方式在皮内可控释放药物治疗真菌病如甲癣等。 3.金属二茂钴聚合物的合成(通过RAFT聚合, ATRP聚合,和ROP开环聚合等聚合方法)及其在抗菌方面的应用。
【近5年来代表性论文】 1.Peng Yang,‡Shih-Jie Chou,‡Jindian Li, Wenqiao Hui, Wenfei Liu, Na Sun, Ryan Y. Zhang, Yazhen Zhu, Matthew Smalley, Jiayuan Chen, Zulema Romero, Dahai Liu, Zunfu Ke, Chang Zou, Chin-Fa Lee, Steve J. Jonas, Qian Ban,* Paul S. Weiss,* Donald B. Kohn,* Kai Chen,* Shi-Hua Chiou* and Hsian-Rong Tseng* Supramolecular Nanosubstrate-Mediated Delivery System Enables CRISPR/Cas9 Knockin of Hemoglobin Beta Gene for Hemoglobinopathies.Science Advances,2020,6, eabb7107. 2.Peng Yang,Yuanyuan Luo, Leman B. Kurnaz, Marpe Bam, Xiaoming Yang, Alan W. Decho, Mitzi Nagarkatti, and Chuanbing Tang* Biodegradable Polycaprolactone Metallopolymer-Antibiotic Bioconjugates Containing Phenylboronic Acid and Cobaltocenium for Antimicrobial Application.Biomaterials Science,2021,9,7237-7246. 3.Qian Ban,‡Peng Yang,‡Shih-Jie Chou,Li Qiao,Haidong Xia,Jingjing Xue,Fang Wang,Xiaobin Xu,Na Sun,Ryan Y. Zhang,Ceng Zhang,Athena Lee,Wenfei Liu,Ting-Yi Lin,Yu-Ling Ko,Petar Antovski,Xinyue Zhang,Shih-Hwa Chiou, Chin-Fa Lee,* Wenqiao Hui,* Dahai Liu,* Steve J. Jonas,* Paul S. Weiss,* and Hsian-Rong Tseng* Supramolecular Nanosubstrate-Mediated Delivery Strategy for CRISPR/Cas9 Gene Disruption and Deletion.Small2021, 2100546. (‡Equal contribution) 4.Shih-Jie Chou,‡Peng Yang,‡Qian Ban, Yi-Ping Yang, Mong-Lien Wang, Chian-Shiu Chien, Paul S. Weiss,* Hsian-Rong Tseng* and Shi-Hua Chiou* Dual Supramolecular Nanoparticle Vectors Enable CRISPR/Cas9-Mediated Knockin of Retinoschisin 1 Gene—A Potential Nonviral Therapeutic Solution for X-Linked Juvenile Retinoschisis.Advanced Science2020, 1903432.(‡Equal contribution,highlighted as aFrontispiece,) 5.Fang Wang,‡Peng Yang,‡Jin-sil Choi, Petar Antovski, Yazhen Zhu, Xiaobin Xu, Ting-Hao Kuo, Li-En Lin, Diane N.H. Kim, Pin-Cheng Huang, Haoxiang Xu, Chin-Fa Lee, Changchun Wang,* Cheng-Chih Hsu,* Kai Chen,* Paul S. Weiss,* and Hsian-Rong Tseng* Cross-Linked Fluorescent Supramolecular Nanoparticles for Intradermal Controlled Release of Antifungal Drug – A Therapeutic Approach for Onychomycosis.ACS Nano2018, 12, 6851-6859. (‡Equal contribution) 6.Peng Yang, Paras Pageni,Marpe Bam, Yungpin Chen, Mitzi Nagarkatti, Alan Decho and Chuanbing Tang* Gold Nanoparticles with Antibiotic-Metallopolymers toward Broad-Spectrum Antibacterial Effects..Advanced Healthcare Materials2019,8,1800854. 7.Peng Yang, Paras Pageni, Pabel Kabir, Tianyu Zhu and Chuanbing Tang* Metallocene-Containing Homopolymers and Heterobimetallic Block Copolymers via Photo-Induced RAFT Polymerization.ACS Macro Letters2016, 5, 1293-1300. 8.Peng Yang,Xianfu Luo, Sheng Wang, Fang Wang, and Changchun Wang* Biodegradable Yolk-Shell Microspheres for Ultrasound/MR Dual-Modality Imaging and Controlled Drug Delivery.Colloids and Surfaces B.2017,15, 333-343. 9.Peng Yang, Marpe Bam, Paras Pageni, Yungpin Chen, Mitzi Nagarkatti, Alan Decho, and Chuanbing Tang* Trio Act of Boronolectin with Antibiotic-Metal Complexed Macromolecules toward Broad-Spectrum Antimicrobial Efficacy.ACS Infectious Diseases,2017, 3, 845-853.
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