新利18体育官网登录网址情况简介 |
【近年来获得的学术科研成果】 主持了国家自然科学基金、江苏省自然科学基金、江苏省“双创计划”、教育部留学回国人员基金、企业横向合作课题等资助项目；申请与授权专利10项，专利转让1项；科研成果获中国商业联合会科技进步奖。到目前为止，已经在Chemical Communications, Journal of Enzyme Inhibition & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters等国内外学术刊物发表论文80余篇。
【近年来主要研究课题】 [1]2020年度无锡市科技发展资金项目 [2]2019年度无锡市医疗与公众健康技术创新应用项目 [3]2018年江苏省“双创团队”资助经费（核心成员） [4]霍英东教育基金会高等院校青年教师基金 [5]企业横向合作课题 [6]江苏省"六大人才高峰"计划资助项目 [7]无锡市留学人员科技活动项目择优资助重点项目 [8]教育部留学回国人员科研启动基金
【近年来主要论文代表作】 [1]Shang, M.D.; Wu, Y.Y.; Wang, Y.Y; Cai, Y.F.; Jin, J.*; Yang, Z.Q.*Dual antisense oligonucleotide targeting miR-21/miR-155 synergize photodynamic therapy to treat triple-negative breast cancer and inhibit metastasis.Biomed. Pharmacother., 2022, 146, 112564. [2]Gong, S.Y.;Shang, M.D.; Li, D.W.; Cai, Y.F.; Jin, J.*; Yang, Z.Q.*Functionalized ZIF-90 for gene-mediated chemotherapy to ameliorate drug resistance in breast cancer.ChemNanoMat, 2022, 8(2), e202100389. [3]Li, Q.X.; Kang, Y.;Yin, S.X.;Qian, Y.; Cai, Y.F.; Yang, Z.Q.*Graphene oxide synergy with the conjugation of DNA and quantum dots for the sensitive detection of Ochratoxin A.Food Anal. Method,2022, 15, 440-447. [4]Han, Z.Y.;Qian, Y.; Wu, Y.Y.; Cai, Y.F.; Jin, J.*; Yang, Z.Q.*Metal-organic frameworks deliver the conjugate of functional oligonucleotides and photosensitizer to induce apoptosis for enhancing chemotherapy.ChemNanoMat, 2021, 7(12), 1361-1368. [5]Qin, L.;Yang, D.T.; Yin, S.X.;Qian, Y.; Cai, Y.F.; Jin, J.; Huang, G.;*Yang, Z.Q.*Graphene Oxide Biosensors Based on Hybridization Chain Reaction Signal Amplification for Detecting Biomarkers of Radiation-Resistant Nasopharyngeal Carcinoma and Imaging in Living Cells.Langmuir, 2021, 37, 9664-9672. [6]Yang, Z.Q.*; Yang, D.T.; Zeng, K.; Li, D.R.; Qin, L.; Cai, Y.F.; Jin, J.*Simultaneous Delivery of antimiR-21 and Doxorubicin by Graphene Oxide for Reducing Toxicity in Cancer Therapy.ACS Omega, 2020, 5, 14437-14443. [7]Yang, Z.Q.*; Qin, L.; Yang, D.T.; Chen, W.X.; Qian, Y.; Jin, J.*Investigating Adsorption /Desorption of DNA on ZIF-8 Surface by Fluorescently Labeled Oligonucleotides.Langmuir,2019, 35, 49, 16290-16296. [8]Yang, Z.Q.*; Qin, L.; Yang, D.T.; Chen, W.X.; Qian, Y.; Jin, J.*Signal amplification method for miR-205 assay through combining graphene oxide with duplex-specific nuclease.RSC Adv.,2019, 9, 27341–27346. [9]Yang, Z.Q.*; Hu, Q.X.; Qin, L.; Zhu, S.Y.; Qiu, L.Y.; Su, Y.X.; Jin, J.*RNase H amplified RNA probe and graphene oxide system for highly sensitive detection of (CAG)n DNA repeat sequences.Nanotechnology, 2019, 30, 465502. [10]Yang, Z.Q.*; Qin, L.; Yang, D.T.; Hu, Q.X.; Jin, J.*A graphene oxide fluorescent sensing platform for sensitive and specific detecting biomarker of radiation-resistant nasopharyngeal carcinoma.Bioorg. Med. Chem. Lett., 2019, 29(16), 2383-2386.
【近年来主要申请与授权国家发明专利】 [1]大豆提取物Bowman-Birk inhibitor切割DNA的方法 [2]一种利用RNase H检测(CAG)n重复序列的方法 [3]一种基于亚麻环肽A切割DNA的方法 [4]一种细菌I型拓扑异构酶的抑制剂及其应用 [5]一种用于检测赭曲霉毒素A的生物传感器的制备方法
【主要获得奖励与荣誉称号】 [1]2021年中国商业联合会科技进步奖二等奖 [2]2020年中国商业联合会科技进步奖三等奖 [3]江苏省双创团队核心成员 [4]教育部霍英东教育基金会高等院校青年教师基金（现霍英东青年科学奖） [5]江苏省“六大人才高峰”计划 [6]2015年中国商业联合会科技进步奖一等奖 [7]江苏省“博士集聚计划(境外世界名校创新类)” [8]无锡市社会事业领军人才 |
